Certain Canadian provinces have their own Business Immigration programs within their Provincial Nomination Programs (PNP) to nominate applicants for Permanent Residency.
Canada and its Provinces have entered into agreements allowing a person to be nominated by the Provincial Government and to be issued an Immigrant Visa without having to meet the pass mark required for skilled workers and business immigrants. As a result, individual Provinces are responsible for issuing nomination certificates. Suppose you are successful in convincing a Province that you have a skill or business in high demand for that particular Province. In that case, the Province will issue you a certificate, provided that you meet all other statutory and admissibility requirements of Citizenship and Immigration Canada and that you can become economically established. You will then be issued an Immigrant Visa for entry into Canada.
You need to understand the application options about how you need to apply depending on which Provincial Nominee stream you are applying to. You may need to apply using a paper-based process or by the online Express Entry. No matter where you live in Canada, you will have to pass a medical exam and get a police check certificate as part of this process.